![]() The Devil Room may also be accessed via the Joker Suit. There are multiple factors that increase the chances of a Devil Room spawning, such as possessing a Pentagram, killing a Beggar, etc. Unlocked after beating It Lives! It is also possible to access it early on through an Angel Room after beating Mom's Heart/It Lives! The final boss of the Cathedral will always be Isaac. The Devil Room is a special Room that has a chance to appear after defeating a boss, although it is rare. It is a room where a player can find Black Hearts, Red Chests, and trade Isaac's hearts and soul hearts for Collectibles. The door will also open by using the Dad's Key usable item. A Devil Room is a room in The Binding of Isaac: Rebirth. The Binding of Isaac: Epiphany is a mod that aims to add a new variant for all characters in Repentance, called 'Ta. If you have a Golden Key (achieved by killing two Angel mini-bosses in Angel Rooms), then the door will open and you will be able to fight the Mega Satan boss fight. ![]() After beating The Lamb for the first time, a golden door will appear in the starting room of the Dark Room floor. The final boss of the Dark Room will always be The Lamb. It is also possible to access it early on through a Devil Room after beating Mom's Heart/It Lives! The final boss of Sheol will always be Satan.Ĭan only be entered by beating Satan in Sheol and touching the chest while having The Negative item. The final boss of the Womb/Utero will always be Mom's Heart/It Lives! To unlock Utero, you must beat every possible boss on the Womb floor. Every floor at this point in the game will double any half-heart damage dealt against you to full heart damage (this includes Curse Rooms).
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